A new study being published in the upcoming issue of the journal CNS & Neurological Disorders – Drug Targets, and published online by the National Institute of Health, has found that cannabidiol (CBD) can treat newborn brain damage, and can do so when administered longer after a dramatic event than other treatment options.
According to the study’s abstract, its purpose was “to test the TTW [therapeutic time window] of the neuroprotective effects of cannabidol (CBD), a non-psychoactive cannabinoid in a model of newborn HI brain damage.”
In doing so, researchers administered CBD to newborn mice with brain damage; it was administered 15 minutes after the induction of brain damage, and then 1, 3, 6, 12, 18 and 24 hours after.
Researchers found that “CBD administered up to 18 h after HI [hypoxic-ischemic brain damage] reduced IHVL and neuropathological score by 60%, TUNEL+ count by 90% and astrocyte damage by 50%. In addition, CBD blunted the HI-induced increase in microglial population.”
However, when CBD administration was delayed 24 hours, these effects were greatly reduced.
The study concludes; “CBD shows a TTW of 18 h when administered to HI newborn mice, which represents a broader TTW than reported for other neuroprotective treatments including hypothermia.”
The full study can be found on the National Institute of Health’s website by clicking here.
About Anthony Martinelli
Anthony, co-founder and Editor-in-Chief of TheJointBlog, has worked closely with numerous elected officials who support cannabis law reform, including as the former Campaign Manager for Washington State Representative Dave Upthegrove. He has also been published by multiple media outlets, including the Seattle Times. He can be reached at TheJointBlog@TheJointBlog.com.